Greenpoint is the northernmost neighborhood in the New York City borough of Brooklyn, in the U.S. state of New York. It is bordered on the southwest by Williamsburg at Bushwick Inlet Park and McCarren Park; on the southeast by the Brooklyn–Queens Expressway and East Williamsburg; on the north by Newtown Creek and the neighborhood of Long Island City in Queens; and on the west by the East River. The neighborhood has a large Polish immigrant and Polish-American community, containing many Polish restaurants, markets, and businesses, and it is often referred to as Little Poland.

Originally farmland—many of the farm owners’ family names, such as Meserole (Messerole) and Calyer, are current street names—the residential core of Greenpoint was built on parcels divided during the Industrial Revolution and late 19th century, with rope factories and lumber yards lining the East River to the west, while the northeastern section along the Newtown Creek through East Williamsburg became an industrial maritime area.

Greenpoint has long held a reputation of being a working class and immigrant neighborhood, and it initially attracted families and workers with its abundance of factory jobs, heavy industry and manufacturing, shipbuilding, and longshoreman or dock work. Since the early 2000s, a building boom in the neighborhood has made the neighborhood increasingly a center of nightlife and gentrification, and a 2005 rezoning enabled the construction of high density residential buildings on the East River waterfront. There have also been efforts to reclaim the rezoned East River waterfront for recreational use and also to extend a continuous promenade into the Newtown Creek area.

Greenpoint is part of Brooklyn Community District 1, and its primary ZIP Code is 11222. It is patrolled by the 94th Precinct of the New York City Police Department.